MatchaDB

Research topic

Matcha and cancer research

Researchers have studied matcha extracts and EGCG in cancer cell lines (oral, breast and others) and in animal models, and several reviews summarize the wider green tea evidence.

Most matcha-specific work is preclinical. These papers describe mechanisms in cells and animals, not treatments.

32

studies

1985–2026

years covered

19

from the last five years

23

free to read

What kind of evidence is this?

  • Animal study9
  • In vitro / cell study7
  • Review4
  • Chemical / analytical3
  • Systematic review / meta-analysis2
  • Sensory / consumer2
  • Not classified (no abstract)2
  • Other / not stated1
  • Observational (human)1
  • Randomized controlled trial1

A result in cultured cancer cells is a starting point for further research, not evidence that matcha prevents or treats cancer.

Common keywords

green tea 8antioxidants 6mcf-7 cells 6camellia sinensis 5epigallocatechin gallate 5cytotoxicity 5breast cancer 5cell proliferation 5catechins 4apoptosis 4oxidative stress 4matcha tea 4bladder cancer 4antioxidant activity 3

Most recognized studies on this topic

Ranked by recency, citations, journal standing and study design.

2026Journal article

Dietary Beverages and Cutaneous Health: Mechanisms, Clinical Evidence, and Practical Implications for Dermatologists.

Unsal G, Karadag AS, Hoenig LJ — Clinics in dermatology

Background: Beverage consumption is a common, modifiable lifestyle factor with potential relevance to cutaneous health. Objective: To synthesize clinical and mechanistic evidence on commonly consumed beverages and dermatological outcomes.…

Systematic review / meta-analysisCancerSkin, oral and dentalFood products and applicationsCited 1×
2021Journal articleFree to read

Powdered Green Tea (Matcha) Attenuates the Cognitive Dysfunction via the Regulation of Systemic Inflammation in Chronic PM2.5-Exposed BALB/c Mice.

Kim JM, Kang JY, Park SK, et al. — Antioxidants (Basel, Switzerland)

This study was conducted to evaluate the anti-amnesic effect of the aqueous extract of powdered green tea (matcha) (EM) in particulate matter (PM)2.5-induced systemic inflammation in BALB/c mice. EM ameliorated spatial learning and memory…

Animal studyCognition, mood and stressAntioxidants and polyphenolsCancerCited 34×
2025Journal articleFree to read

Assessing the influence of matcha green tea extract on NF-κB/MAPK signaling pathway activation in rats: A study on irradiation-induced acute hepatic inflammatory response

Noha Sayed Hamed, Eithar Karem El-Adham, Amal I. Hassan — Phytomedicine Plus

Background Numerous forms of cancer are frequently treated with radiation therapy, which provides substantial benefits in tumor control. However, adverse effects, particularly the development of severe hepatitis, may render radiation…

Animal studyMetabolism and weightAntioxidants and polyphenolsInflammation and immunityCited 4×
2026Journal articleFree to read

From coffee to matcha: decoding the multidimensional competence of matcha as a sustainable and health-promoting coffee substitute.

Hu H, Zhang H, Liu Z, et al. — Journal of the science of food and agriculture

This review provides a comprehensive analysis of the bioactive compounds, health benefits, and production processes of two globally popular stimulant beverages: coffee and matcha. Both beverages are rich in bioactive compounds such as…

ReviewCognition, mood and stressAntioxidants and polyphenolsL-theanine and caffeineCited 1×
2022Journal articleFree to read

Prospective Medicinal Plants and Their Phytochemicals Shielding Autoimmune and Cancer Patients Against the SARS-CoV-2 Pandemic: A Special Focus on Matcha.

Kiriacos CJ, Khedr MR, Tadros M, et al. — Frontiers in oncology

Background: Being "positive" has been one of the most frustrating words anyone could hear since the end of 2019. This word had been overused globally due to the high infectious nature of SARS-CoV-2. All citizens are at risk of being…

ReviewAntioxidants and polyphenolsCancerInflammation and immunityCited 10×
2026Journal articleFree to read

UPLC profiling of matcha extract capping biosynthesized copper oxide nanoparticles and their antimicrobial and cytotoxic potentials.

Batouti ME, Al-Harby NF, Abdelwahab MS, et al. — Scientific reports

This research demonstrates a green synthesis and subsequent functionalization process of copper oxide nanoparticles (CuO NPs) utilizing matcha green tea extract as a sustainable reducing and functionalizing agent. UPLC-MS analysis revealed…

In vitro / cell studyAntioxidants and polyphenolsCancerInflammation and immunityCited 1×
2019Journal articleFree to read

Effects of green tea, matcha tea and their components epigallocatechin gallate and quercetin on MCF‑7 and MDA-MB-231 breast carcinoma cells.

Schröder L, Marahrens P, Koch JG, et al. — Oncology reports

We investigated the anticarcinogenic potential of green tea and its components epigallocatechin gallate (EGCG) and quercetin, as well as tamoxifen, on MCF-7 and MDA-MB-23 breast cancer cells. Using high-performance liquid chromatography,…

In vitro / cell studyAntioxidants and polyphenolsCancerInflammation and immunityCited 76×
2026Journal articleFree to read

Cosmeceutical Potential of Matcha (Camellia sinensis) and Yerba Mate (Ilex paraguariensis) Extracts Obtained with Green Solvents.

Gaweł-Bęben K, Szczepanik M, Szczeblewski P, et al. — Molecules (Basel, Switzerland)

Matcha (Camellia sinensis) and yerba mate (Ilex paraguariensis) are polyphenol-rich plants of growing interest for cosmetic applications, yet the influence of green extraction solvents on their cosmeceutical potential remains…

In vitro / cell studyAntioxidants and polyphenolsSkin, oral and dentalAuthenticity and analytical methods
2022Journal articleFree to read

Effects of matcha tea extract on cell viability and peroxisome proliferator-activated receptor γ expression on T47D breast cancer cells.

Keckstein S, Tilgener C, Jeschke U, et al. — Archives of gynecology and obstetrics

Purpose: In the following work, we investigated the nuclear peroxisome proliferator-activated receptor gamma (PPARγ)-dependent proliferation behavior of breast cancer cells after stimulation with matcha green tea extract (MTE). Methods:…

Chemical / analyticalCancerCited 11×
Search all 32 studies on this topic

Newest research

2026Journal articleFree to read

Cosmeceutical Potential of Matcha (Camellia sinensis) and Yerba Mate (Ilex paraguariensis) Extracts Obtained with Green Solvents.

Gaweł-Bęben K, Szczepanik M, Szczeblewski P, et al. — Molecules (Basel, Switzerland)

Matcha (Camellia sinensis) and yerba mate (Ilex paraguariensis) are polyphenol-rich plants of growing interest for cosmetic applications, yet the influence of green extraction solvents on their cosmeceutical potential remains…

In vitro / cell studyAntioxidants and polyphenolsSkin, oral and dentalAuthenticity and analytical methods
2026Journal article

Dietary Beverages and Cutaneous Health: Mechanisms, Clinical Evidence, and Practical Implications for Dermatologists.

Unsal G, Karadag AS, Hoenig LJ — Clinics in dermatology

Background: Beverage consumption is a common, modifiable lifestyle factor with potential relevance to cutaneous health. Objective: To synthesize clinical and mechanistic evidence on commonly consumed beverages and dermatological outcomes.…

Systematic review / meta-analysisCancerSkin, oral and dentalFood products and applicationsCited 1×
2026Journal articleFree to read

From coffee to matcha: decoding the multidimensional competence of matcha as a sustainable and health-promoting coffee substitute.

Hu H, Zhang H, Liu Z, et al. — Journal of the science of food and agriculture

This review provides a comprehensive analysis of the bioactive compounds, health benefits, and production processes of two globally popular stimulant beverages: coffee and matcha. Both beverages are rich in bioactive compounds such as…

ReviewCognition, mood and stressAntioxidants and polyphenolsL-theanine and caffeineCited 1×
2026Journal articleFree to read

UPLC profiling of matcha extract capping biosynthesized copper oxide nanoparticles and their antimicrobial and cytotoxic potentials.

Batouti ME, Al-Harby NF, Abdelwahab MS, et al. — Scientific reports

This research demonstrates a green synthesis and subsequent functionalization process of copper oxide nanoparticles (CuO NPs) utilizing matcha green tea extract as a sustainable reducing and functionalizing agent. UPLC-MS analysis revealed…

In vitro / cell studyAntioxidants and polyphenolsCancerInflammation and immunityCited 1×

Related topics

Antioxidants and polyphenolsStudies measuring matcha's catechins, EGCG, chlorophyll and other polyphenols, how much they vary, and how they hold up in processing and storage.Inflammation and immunityCell, animal and human studies on matcha's effects on inflammation markers and immune function.Skin, oral and dentalStudies on matcha and green tea catechins in skin care, oral bacteria, gum health and dental applications.

This page describes what published studies examine; it is not medical advice, and a study being listed is not an endorsement of its findings. Topic tags and study types are assigned automatically from each paper's text (see how the library is built). Library last rebuilt October 20, 2026.