MatchaDB

2026Journal articleFree to read

Matcha Supplementation Attenuates High-Fat, High-Sugar Diet–Induced Cardiomyocyte Hypertrophy by Reshaping the Gut Microbiota in Mice

Cody Moss, Gopal Lamichhane, Jong-Beom Jin, Jiaqing Guo, Da‐Yeon Lee, Jiyoung Bae, Guolong Zhang, Yoo Kim

Current Developments in Nutrition

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Abstract

Objectives: Matcha, a powdered form of green tea, is rich in bioactive compounds, including L-theanine and polyphenols, that have been associated with beneficial effects on cardiometabolic and gut health. This study aimed to evaluate whether dietary matcha supplementation attenuates high-fat, high-sugar diet (HFHSD)–induced cardiac hypertrophy and whether these effects are related to alterations in the gut microbiota along the gut-heart axis.

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Study type

Animal study

Experiments in mice, rats, fish or other animals.

Assigned automatically from the title, abstract and subject terms.

Keywords and subject terms

Cite this study

Cody Moss, Gopal Lamichhane, Jong-Beom Jin, Jiaqing Guo, Da‐Yeon Lee, Jiyoung Bae, … Yoo Kim. (2026). Matcha Supplementation Attenuates High-Fat, High-Sugar Diet–Induced Cardiomyocyte Hypertrophy by Reshaping the Gut Microbiota in Mice. Current Developments in Nutrition. https://doi.org/10.1016/j.cdnut.2026.108484

DOI: 10.1016/j.cdnut.2026.108484

More on metabolism and weight

2023Journal article

Monitoring chlorophyll changes during Tencha processing using portable near-infrared spectroscopy.

Liu L, Zareef M, Wang Z, et al. — Food chemistry

Monitoring chlorophyll during Tencha (the raw ingredient for matcha) processing is critical for determining the matcha's color and quality. The purpose of this study is to explore the mechanism of chlorophyll changes during Tencha…

Chemical / analyticalCultivation and shadingProcessing, milling and qualityAuthenticity and analytical methodsCited 91×
2020Journal article

Changes in Intestinal Microbiota of Type 2 Diabetes in Mice in Response to Dietary Supplementation With Instant Tea or Matcha.

Zhang HH, Liu J, Lv YJ, et al. — Canadian journal of diabetes

Objective: Gut microbiota plays a key role in metabolism and health in diabetes patients with gastrointestinal microbiota dysbiosis. Thus, regulating the ecological balance of gut microbiota may provide a pathway toward improvement for…

Animal studyMetabolism and weightGut and microbiomeMarket, culture and sustainabilityCited 68×
2018Journal articleFree to read

Matcha green tea (MGT) inhibits the propagation of cancer stem cells (CSCs), by targeting mitochondrial metabolism, glycolysis and multiple cell signalling pathways.

Bonuccelli G, Sotgia F, Lisanti MP — Aging

Matcha green tea (MGT) is a natural product that is currently used as a dietary supplement and may have significant anti-cancer properties. However, the molecular mechanism(s) underpinning its potential health benefits remain largely…

In vitro / cell studyMetabolism and weightAntioxidants and polyphenolsCancerCited 66×

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