MatchaDB

2026Journal articleFree to read

The Impact of Matcha Green Tea on Human Health – Mechanisms of Action, Clinical Evidence, and Health Effects

Bartosz Wróbel, Lena Wójcik, Michał Filipski, Kuba Ptaszkiewicz, Filip Basta

Quality in Sport

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Abstract

Matcha green tea, a powdered whole-leaf preparation from shade-grown Camellia sinensis, exhibits a unique biochemical profile rich in catechins (particularly EGCG), L-theanine, caffeine, and chlorophyll, distinguishing it from conventional green teas. This narrative review synthesizes evidence on matcha's composition, mechanisms of action, and health effects. Mechanistically, EGCG activates the Nrf2/Keap1 antioxidant pathway, suppresses inflammatory signaling, and synergizes with L-theanine/caffeine to enhance cognitive function, while modulating gut microbiota toward beneficial taxa like Coprococcus. Clinical and preclinical studies demonstrate cardiometabolic benefits including improved glycemic control, lipid profiles, and hepatic protection against NAFLD, alongside cognitive enhancements and reduced exercise-induced fatigue. Preliminary data suggest anti-cancer potential via apoptosis induction and metabolic inhibition in tumor cells. Despite promising mechanistic insights, human trials remain limited by small samples, short durations, and heterogeneous preparations. Matcha emerges as a functional food with multifaceted health potential, warranting large-scale randomized controlled trials to establish optimal dosing, long-term efficacy, and safety for evidence-based recommendations.

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Study type

Randomized controlled trial

People were randomly assigned to matcha or a comparison.

Assigned automatically from the title, abstract and subject terms.

Keywords and subject terms

Cite this study

Bartosz Wróbel, Lena Wójcik, Michał Filipski, Kuba Ptaszkiewicz, Filip Basta. (2026). The Impact of Matcha Green Tea on Human Health – Mechanisms of Action, Clinical Evidence, and Health Effects. Quality in Sport. https://doi.org/10.12775/qs.2026.54.70607

DOI: 10.12775/qs.2026.54.70607

More on cognition, mood and stress

2020Journal articleFree to read

Health Benefits and Chemical Composition of Matcha Green Tea: A Review.

Kochman J, Jakubczyk K, Antoniewicz J, et al. — Molecules (Basel, Switzerland)

Japanese matcha is a type of powdered green tea, grown in a traditional way. Shading of the plants during the growth period enhances the processes of synthesis and accumulation of biologically active compounds, including theanine,…

ReviewCognition, mood and stressAntioxidants and polyphenolsL-theanine and caffeineCited 321×
2018Journal articleFree to read

Stress-Reducing Function of Matcha Green Tea in Animal Experiments and Clinical Trials.

Unno K, Furushima D, Hamamoto S, et al. — Nutrients

Theanine, a major amino acid in green tea, exhibits a stress-reducing effect in mice and humans. Matcha, which is essentially theanine-rich powdered green tea, is abundant in caffeine. Caffeine has a strong antagonistic effect against…

Randomized controlled trialCognition, mood and stressAntioxidants and polyphenolsL-theanine and caffeineCited 84×
2017Journal articleFree to read

An intervention study on the effect of matcha tea, in drink and snack bar formats, on mood and cognitive performance.

Dietz C, Dekker M, Piqueras-Fiszman B — Food research international (Ottawa, Ont.)

Matcha tea is gaining popularity throughout the world in recent years and is frequently referred to as a mood-and-brain food. Previous research has demonstrated that three constituents present in matcha tea, l-theanine, epigallocatechin…

Randomized controlled trialCognition, mood and stressAntioxidants and polyphenolsL-theanine and caffeineCited 66×

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